Cell-free product that is immune privileged and can be administered to any recipient without the need for immunosuppressive medications.
Modulates immune cells called macrophages to express healing properties.
Product formulations have been intelligently tailored to the clinical application factored together with practical, patient-centered, considerations for its therapeutic delivery.
Produced as an injectable particulate or patch where the sizes can be easily tuned, depending on the clinical application.
Particulate formulation is compatible with 27G or larger bore needles including long, steerable, needle-tipped catheters both injected alone and in combination with stem cells.
Binds effectively to all cells, including stem cells. These bonds improve the retention of injected stem cells by preventing their rapid egress via vasculature and lymphatics in the beating heart.
Thin, pliable patch formulation, which is currently a little larger than a contact lens, is easily handled by surgeons during application on the heart surface. Applied as a patch does not require sutures or glue.
Constituent proteins are well-defined, and our production methods yield a highly reproducible, scalable product that is shelf-stable at room temperature, and that is ready to transition to a cGMP manufacturing facility.
